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Some scientists even proposed that GLP-1 should be used in Alzheimer’s disease to control the symptoms, but more studies are required on this matter
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Abbreviations: AMPK AMP-activated protein kinase CCK cholecystokinin CGRP Calcitonin gene-related peptide DPP IV dipeptidyl-peptidase IV EPAC exchange protein directly activated by cAMP ERK1/2 extracellular signal-regulated kinases GIP glucose-dependent insulinotropic polypeptide GLP-1 Glucagon-like peptide-1 GLP-1r Glucagon-like peptide-1 receptor GLP-1 EECs enteroendocrine GLP-1 producing cells GPCRs G protein-coupled receptors IP 3 inositol triphosphate MAPK mitogen-activated protein kinase mTOR mechanistic target of rapamycin NTS nucleus of the solitary tract PBN parabrachial nucleus PI3K phosphatidylinositol 3-kinase PKC protein kinase C PLC phospholipase C POMC proopiomelanocortin SGLT sodium coupled glucose transporters VGCCs voltage gated calcium channels References Ahrén B, 2004
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